Trichuris trichiura egg extract proteome reveals potential diagnostic targets and immunomodulators
نویسندگان
چکیده
منابع مشابه
Colonoscopic diagnosis of cecal worms (Trichuris trichiura)
Two unrelated Bangladeshi women, a 61-year-old with chronic diarrhea, lower abdominal pain, poor appetite, and weight loss for two years with normal physical exam and unremarkable laboratory tests; and a 58-year-old with epigastric pain, bloating, poor appetite, weight loss for three months, and iron-defi ciency anemia, presented for colonoscopy. Colonoscopy revealed two white-colored worms in ...
متن کاملThe public health significance of Trichuris trichiura.
An estimated 1049 million persons harbour T. trichiura, including 114 million preschool-age children and 233 million school-age children. The prevalence of T. trichiura is high and may reach 95% in children in many parts of the world where protein energy malnutrition and anaemias are also prevalent and access to medical care and educational opportunities is often limited. The Trichuris dysenter...
متن کاملOxantel pamoate-albendazole for Trichuris trichiura infection.
BACKGROUND Infections with soil-transmitted helminths (Ascaris lumbricoides, hookworm, and Trichuris trichiura) are widespread and often occur concomitantly. These parasitic-worm infections are typically treated with albendazole or mebendazole, but both drugs show low efficacy against T. trichiura. Albendazole is the drug of choice against hookworm. METHODS In this double-blind trial conducte...
متن کاملA proteomic approach to identify proteins from Trichuris trichiura extract with immunomodulatory effects.
Infections with Trichuris trichiura and other trichurid nematodes have been reported to display protective effects against atopy, allergic and autoimmune diseases. The aims of the present study were to investigate the immunomodulatory properties of T. trichiura adult worm extract (TtE) and its fractions (TtEFs) on the production of cytokines by peripheral blood mononuclear cells and to identify...
متن کاملErratum: Trichuris trichiura in a post-Colonial Brazilian mummy
Trichuris trichiura is a soil-transmitted helminth which is prevalent in warm, moist, tropical and subtropical regions of the world with poor sanitation. Heavy whipworm can result either in Trichuris dysenteric syndrome - especially in children - or in a chronic colitis. In heavy infections, worms can spread proximally and may cause ileitis. Here we provide first microscopic evidence for a T. t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLOS Neglected Tropical Diseases
سال: 2021
ISSN: 1935-2735
DOI: 10.1371/journal.pntd.0009221